Antihypertensive benzopyran derivatives

Details Antihypertensive benzopyran derivatives Antihypertensive benzopyran derivatives

1991-10-08

1992-12-15

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548484, C07D47104

Patent

active

051718570

ABSTRACT:
Disclosed herein are novel benzopyrans represented by formula (I) ##STR1## wherein R.sup.1 is trifluoromethoxy or .beta., .beta., .beta.-trifluoroethoxy; R.sup.2 and R.sup.3 are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 5 carbon atoms, cyclo lower alkyl containing 5 to 8 carbon atoms, ##STR2## or R.sup.2 and R.sup.3 are joined to form (--CH.sub.2 --).sub.n wherein n is 4 to 7; or R.sup.2 and R.sup.3 are joined together to form (--CH.sub.2 --).sub.m CO-- wherein m is 3 to 6; or R.sup.2 and R.sup.3 are joined together to form ##STR3## wherein R.sup.4 is selected from the group consisting of hydrogen, alkoxy containing 1 to 5 carbon atoms, amino or mono- or disubstituted alkyl amino wherein said alkyl groups contain 1 to 5 carbon atoms and the pharmaceutically acceptable salts and solvates thereof, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in the treatment of hypertension, asthma, irritable bladder syndrome, and irritable bowel syndrome.

REFERENCES:
patent: 4616021 (1986-10-01), Ashwood et al.

Affiliated with

Also associated with

Rating

Antihypertensive benzopyran derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antihypertensive benzopyran derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antihypertensive benzopyran derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2094224