Antihypertensive agents and process for producing the same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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A61K 3578

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active

045101612

ABSTRACT:
An aqueous extract product which is effective for prevention or treatment of hypertension is produced by: concentrating an aqueous extract obtained by: extracting water-soluble components from vegetable oils such as soybean oil, corn oil, rapeseed oil and cotton seed oil; adding a lower alcohol to the resulting extract to prepare an alcoholic solution having an alcohol concentration above 85%, thereby precipitating the insoluble matter; then removing the precipitates; and thereafter removing the alcohol. A powdered product having an antihypertensive activity is also produced by: subjecting said aqueous extract product to an additional optional purification step and thereafter concentrating the resulting product to obtain a powder. An antihypertensive agent containing a novel substance OSG as an effective component is also disclosed.

REFERENCES:
patent: 4154750 (1979-05-01), Moore et al.
Chemical Abstracts, 94:155460q (1981) [Mogenson, G., et al., Nutr. Rep. Int. 1981, 23(3), 411-418].
Chemical Abstracts, 95:181649y (1981) [Tokumura, A., et al., J. Pharmacol. Exp. Ther., 1981, 219(1), 219-224].

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