Antihypertensive agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544 6, 544 13, 2602433, 2601125R, C07D41712, A61K 3154

Patent

active

045593400

ABSTRACT:
There are disclosed benzothiadiazinyl and quinazolinyl substituted carboxylalkyl dipeptides, wherein the benzothiodiazinyl or quinazolinyl portions are joined to the dipeptide portions by an aminocarbonyl group. Compounds of this invention are useful as antihypertensive agents, in the treatment of congestive heart failure and in the treatment of glaucoma. In addition, compounds of this invention have diuretic activity.

REFERENCES:
patent: 4338435 (1982-07-01), Haugwitz
patent: 4431645 (1984-02-01), Smith et al.
patent: 4468396 (1984-08-01), Magatti
Abstract of European Patent Application 95584, Dec. 1983.
Abstract of Australian Patent Application 8, 313,837, Nov. 1983.

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