Antihypertensive 4-amino-2-[4-(substituted-alkoxy)piperidino)]qu

Details Antihypertensive 4-amino-2-[4-(substituted-alkoxy)piperidino)]qu Antihypertensive 4-amino-2-[4-(substituted-alkoxy)piperidino)]qu

1979-04-16

1980-12-02

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544291, 546216, A61K 31505, C07D40104

Patent

active

042371384

ABSTRACT:
Regulators of the cardiovascular system and, in particular, in the treatment of hypertension having the formula ##STR1## pharmaceutically-acceptable bioprecursors thereof, and the pharmaceutically-acceptable acid addition salts thereof; wherein each of R.sup.1 and R.sup.2 is C.sub.1-4 alkyl or --CH.sub.2 CF.sub.3 ; alk is ethylene, monophenyl substituted ethylene, mono- and dimethyl substituted ethylene or monophenylmonomethyl substituted ethylene; and R.sup.3 is hydrogen, C.sub.1-4 alkyl, C.sub.3 -C.sub.6 cycloalkyl; phenyl or substituted phenyl; and methods for their preparation.

REFERENCES:
patent: 3511836 (1970-05-01), Hess

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