Antihypertensive 4-(2-imidazolin-2-yl-amino)-2-methyl-indazole

Details Antihypertensive 4-(2-imidazolin-2-yl-amino)-2-methyl-indazole Antihypertensive 4-(2-imidazolin-2-yl-amino)-2-methyl-indazole

1983-09-07

1985-07-02

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548316, A61K 31415, C07D40312

Patent

active

045268983

ABSTRACT:
4-(2-Imidazolin-2-yl-amino)-2-methyl-indazole is a highly selective and effective .alpha..sub.2 -antagonist, .alpha..sub.1 -partial agonist and .alpha..sub.1s -agonist and displays anti-hypertensive activity and antagonistic activity on adrenaline and noradrenaline. It is useful as an .alpha.-adrenoceptor influencing and as an anti-hypertensively active drug.

REFERENCES:
patent: 4436913 (1984-03-01), Molnar et al.

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