Antihypertensive 4-(2-imidazolin-2-yl-amino)-2-methyl-indazole

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

548316, A61K 31415, C07D40312

Patent

active

045268983

ABSTRACT:
4-(2-Imidazolin-2-yl-amino)-2-methyl-indazole is a highly selective and effective .alpha..sub.2 -antagonist, .alpha..sub.1 -partial agonist and .alpha..sub.1s -agonist and displays anti-hypertensive activity and antagonistic activity on adrenaline and noradrenaline. It is useful as an .alpha.-adrenoceptor influencing and as an anti-hypertensively active drug.

REFERENCES:
patent: 4436913 (1984-03-01), Molnar et al.

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