Antihypertensive 1,5-benzothiazepine derivatives, compositions,

Details Antihypertensive 1,5-benzothiazepine derivatives, compositions, Antihypertensive 1,5-benzothiazepine derivatives, compositions,

1985-07-11

1987-03-31

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540552, A61K 3138, A61K 3155, C07D28110, C07D28108

Patent

active

046543350

ABSTRACT:
Compounds of formula ##STR1## wherein X is S or SO.sub.2, R.sub.4 is aryl or hetero, and R.sub.1 is hydrogen or ##STR2## are disclosed. These compounds are useful as cardiovascular agents and especially as anti-hypertensive agents.

REFERENCES:
patent: 4328238 (1982-05-01), Sato et al.
Medicinal Chemistry, Alfred Burger, 2nd Ed., Interscience Publishers, Inc., N.Y., 1960, pp. 566,568,580,600 and 601.
Merck Index, 10th Edition, p. ONR-50,51 (1983).

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