Antihypertensive 1,5-benzothiazepine derivatives and composition

Details Antihypertensive 1,5-benzothiazepine derivatives and composition Antihypertensive 1,5-benzothiazepine derivatives and composition

1987-07-07

1988-10-25

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540552, A61K 3155, C07D28536

Patent

active

047804629

ABSTRACT:
A new series of 1,5-benzothiazepine analogues are disclosed. These compounds are represented by the following general formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represent hydrogen, a lower alkyl, nitro, amino, lower-alkyl-oxy or halogen group, X represents O or S. These compounds are useful as anti-hypertensive agents.

REFERENCES:
patent: 4584292 (1986-04-01), Tomiyama
Theilheimer, Synthetic Methods of Organic Chemistry, 1952, p. 145, p. 182.

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