Antihyperlipidemic and antiatherosclerotic compounds and composi

Details Antihyperlipidemic and antiatherosclerotic compounds and composi Antihyperlipidemic and antiatherosclerotic compounds and composi

1989-06-09

1990-08-14

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514432, 514450, 514456, 514457, 549 9, 549 23, 549 28, 549355, 549399, 549404, 549407, C07D33700, C07D33504

Patent

active

049488066

ABSTRACT:
Certain N-2,6-dialkyl- or N-2,6-dialkoxyphenyl-N'-arylalkylurea compounds are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT), and are thus useful agents for the treatment of hypercholesterolemia or atherosclerosis.

REFERENCES:
patent: 4868210 (1989-09-01), Trivedi

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