Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-05-05
1988-08-23
Milestone, Norma S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514824, 549292, A61K 31785, A61K 31365, C07D30930
Patent
active
047661453
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
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Chemical Abstract, 87:22516w.
1 Chemical Abstract 86:720290g
1 Chemical Abstract 95:42437q.
Hoffman William F.
Lee Ta J.
Rooney Clarence S.
DiPrima Joseph F.
Merck & Co. , Inc.
Milestone Norma S.
Winokur Melvin
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