Drug – bio-affecting and body treating compositions – Arteriosclerosis
Patent
1988-04-11
1989-07-11
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Arteriosclerosis
514460, 549292, A01N 4316, A61K 31365, C07D30910
Patent
active
048473065
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
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Hoffman William F.
Lee Ta J.
Rooney Clarence S.
DiPrima Joseph F.
Hollrah Glennon H.
Merck & Co. , Inc.
Russell Mark W.
Winokur Melvin
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