Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-06-10
1989-09-05
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549292, 544 59, 544 60, 544149, 544158, 544359, 544389, 546207, 546245, 548518, 548531, 562431, 562496, A61K 31365, C07D30930
Patent
active
048640387
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
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Hoffman William F.
Lee Ta J.
Rooney Clarence S.
DiPrima Joseph F.
Hollrah Glennon H.
Merck & Co. , Inc.
Trinh Ba
Winokur Melvin
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