Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1989-06-14
1991-09-17
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 85, 560117, 560119, 560125, 560126, C07C 6976, C07C 6974, A01N 4316
Patent
active
050496964
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
REFERENCES:
patent: 4376863 (1983-03-01), Lam
patent: 4450171 (1984-05-01), Hoffman et al.
Hoffman William F.
Lee Ta J.
Rooney Clarence S.
DiPrima Joseph F.
Killos Paul J.
Merck & Co. , Inc.
Winokur Melvin
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