Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-01-31
1988-09-20
Milestone, Norma S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549292, 514824, C07D30930, A61K 31365
Patent
active
047726261
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
REFERENCES:
patent: 4375475 (1983-03-01), Willard et al.
patent: 4459422 (1984-07-01), Willard et al.
Smith Robert L.
Stokker Gerald E.
DiPrima Joseph F.
Merck & Co. , Inc.
Milestone Norma S.
Winokur Melvin
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