Antihypercholesterolemic compounds

Details Antihypercholesterolemic compounds Antihypercholesterolemic compounds

1988-05-26

1989-10-24

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514529, 514530, 514531, 514570, 544 59, 544106, 544389, 546190, 546239, 548572, 548579, 549292, 560119, 560123, 560127, C07C 6974, A61K 3119, A61K 31215

Patent

active

048762792

ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.

REFERENCES:
patent: 4024175 (1977-05-01), Satzinger et al.
patent: 4342767 (1982-08-01), Albers-Schonberg et al.
patent: 4351950 (1982-09-01), Sircar
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4618626 (1986-10-01), Skuballe et al.
patent: 4711896 (1987-12-01), Bar-Tana et al.

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