Antihypercholesterolemic compounds

Details Antihypercholesterolemic compounds Antihypercholesterolemic compounds

1982-06-14

1984-05-22

Love, Ethel G.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Synthetic or structurally-modified peptidoglycan or...

549292, 560119, 560256, 424305, 424311, C07C 6974, A61K 31335, C07D30930

Patent

active

044501714

ABSTRACT:
6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H- pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.

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