Antihypercholesterolemic compounds

Details Antihypercholesterolemic compounds Antihypercholesterolemic compounds

1989-06-30

1990-06-26

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

549292, 514460, 514470, 560 9, 560 10, 560 11, 562431, 562496, A61K 31365

Patent

active

049372645

ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.

REFERENCES:
patent: 3231469 (1966-01-01), Canonica
patent: 3546273 (1970-12-01), Bolhofer
patent: 4153803 (1979-05-01), Thiele et al.
patent: 4285951 (1981-08-01), Hoefle
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4448979 (1984-05-01), Terahara et al.

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