Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...
Patent
1980-12-18
1984-04-24
Love, Ethel G.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Synthetic or structurally-modified peptidoglycan or...
549292, 560107, 560185, 560256, 560119, 562501, A61K 31335, C07D30930, C07C 6702
Patent
active
044447841
ABSTRACT:
6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4 (R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.
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Hoffman William F.
Smith Robert L.
Willard Alvin K.
Love Ethel G.
Merck & Co. , Inc.
Monaco Mario A.
Nicholson William H.
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