Antihemophilic factor stabilization

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530416, C07K 302, C07K 322, C07K 1506

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active

052782891

ABSTRACT:
A method of recovering a purified and stabilized protein having antihemophilic factor activity (Factor VIII), from a biological sample containing Factor VIII, at least one destabilizing protease impurity, i.e. thrombin, and optionally one or more proprotease impurity, is provided. The biological sample is contacted with a protease removing and/or inhibiting agent, thereby inhibiting and/or removing the destabilizing protease impurity. The method provides increased yield and resolution of Factor VIII. Also provided are purified and stabilized Factor VIII non-lyophilized, liquid in compositions.

REFERENCES:
patent: 2833691 (1958-05-01), Klaas et al.
patent: 3803115 (1974-04-01), Fekete et al.
patent: 4264471 (1981-04-01), Briggs et al.
patent: 4508709 (1985-04-01), Amphlett et al.
patent: 4522751 (1985-06-01), Linnau et al.
patent: 4743680 (1988-05-01), Mathews et al.
patent: 4965203 (1990-10-01), Silbering et al.
patent: 4970300 (1990-11-01), Fulton et al.

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