Antihemophilic factor

Details Antihemophilic factor Antihemophilic factor

1975-05-01

1976-08-03

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

260112B, 424177, A61K 3514, C07G 7026

Patent

active

039730026

ABSTRACT:
A quick-dissolving antihemophilic factor preparation is obtained by adjusting the pH of buffer-extracted plasma cryoprecipitate to from about pH 6 to about pH 7.0 and cooling to a temperature of from about 2.degree.C to about 20.degree.C for from about 15 minutes to about 1 hour, in order to precipitate certain protein impurities, primarily fibrinogen.

REFERENCES:
patent: 3803115 (1974-04-01), Fekete et al.
Newman et al., British Journal of Haematology, 1971, 21, pp. 1-20.
Johnson et al., British Journal of Haematology, 1971, 21, pp. 21-41.
Weiss et al., British Journal of Haematology, 1970, 18, pp. 89-100.

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