Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-11-07
2006-11-07
Peselev, Elli (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S083000, C514S510000, C514S538000, C536S018100, C552S208000, C552S243000, C552S261000, C552S262000, C552S265000, C552S266000, C552S267000
Reexamination Certificate
active
07132403
ABSTRACT:
Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibitingSchistosomasp. in vitro or in vivo. The preferred anthraquinones have the formula:wherein R1, R2, R3, and R4are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.
REFERENCES:
patent: 4117156 (1978-09-01), Loewe et al.
patent: 5091385 (1992-02-01), Gulliya et al.
patent: 5177073 (1993-01-01), Gulliya et al.
patent: 5489590 (1996-02-01), Gulliya et al.
patent: 6875746 (2005-04-01), Nair et al.
Chemical Abstracts, 130-1100478 (1998).
Chemical Abstracts, 120: 212583 (1994).
Chitsula et al., Acta Trop. 77: 41-51 (2000).
Bica et al., Infect. Dis. Clin. N. Am. 14: 637-642 (2000).
Elliot, Gastroenterol. Clin. N. Am. 25: 599-624 (1996).
Morris and Knauer, Sem. Respir. Infect. 12: 159-170 (1997).
Schafer and Hale, Curr. Gastroenterol. Reports 3: 293-303 (2001).
Cioli, Parasitol. Today 14: 418-422 (1998).
Curr. Opin. Infect Dis. 13: 659-663 (2000).
William et al., Parasitol. 122: 63-66 (2001).
Shiao et al., Acta Pharma. Sinica 9: 218-224 (1962).
Wang et al., Phytochem. 28: 1825-1826 (1989).
Main et al., Aust. Vet. J. 57: 132-135 (1981).
Colegate et al., Aust. J. Chem. 38: 1233-1241 (1985).
Chen et al., Acta. Pharma. Sinica 9: 579-586 (1962).
Khan et al., In Synthesis 255-257 (1994).
Cameron et al., In Tetrahedron Letters 27: 4999-5002 (1986).
Baker and Myers, Pharmacol. Res. 8: 763-770 (1991).
Danielsen and Aksnes, Magn. Reson. Chem. 30: 359-360 (1992).
Schripsema et al., Phytochem. /51: 55-60 (1999).
Li and McLaughlin, J. Nat. Prod. 52: 660-662 (1989).
Midiwo and Arot., Int. J. BioChemiPhysics 2: 115-116 (1993).
Brauers et al., J. Nat. Prod. 63: 739-745 (2000).
Li et al., J. Nat. Prod. 63: 653-656 (2000).
Batterham et al., Aust. J. Chem. 14: 637-642 (1961).
Milovanovic et al., J. Serb. Chem. Soc. 61: 423-429 (1996).
Salter et al., J. Biol. Chem. 275: 38667-38673 (2000).
Cichewicz Robert H.
McKerrow James H.
Nair Muraleedharan G.
Board of Trustees of Michigan State University
McLeod Ian C.
Merritt Steven E.
Peselev Elli
Regents of the University of California
LandOfFree
Antihelminthic anthraquinones and method of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antihelminthic anthraquinones and method of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antihelminthic anthraquinones and method of use thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3697915