Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-05-10
2005-05-10
Wax, Robert A. (Department: 1653)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C424S184100, C424S185100, C436S506000, C436S509000, C436S516000, C530S300000, C530S330000, C530S350000, C530S403000
Reexamination Certificate
active
06890720
ABSTRACT:
The invention concerns an artificial antigen specifically identified by the anti-filaggrin autoantibodies present in the serum of patients suffering from rheumatoid polyarthritis, and consisting of one polypeptide comprising all or part of the sequence of one filaggrin unit or of a related molecule, in which an arginine radical has been substituted by a citrulline radical. The invention also concerns the use of this antigen for diagnosing rheumatoid polyarthritis.
REFERENCES:
patent: 5888833 (1999-03-01), Serre et al.
Arnaud Michel
Dalbon Pascal
Girbal-Neuhauser Elisabeth
Jolivet Michel
Jolivet-Reynaud Colette
Alston & Bird LLP
Biomerieux
Wax Robert A.
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