Antigens comprising immunostimulant adjuvants and their use in i

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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424 88, A61K 3910, A61K 3900

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active

042859301

ABSTRACT:
Antigens are provided which induce relatively large titers of antibodies. These antigens, which may comprise certain strains of microorganisms or a plant extract, can be conjugated to a second antigen by means of an organic coupling agent. The primary antigens of the invention, when chemically coupled to a secondary antigen function as immunostimulant adjuvants. When tumor cells are the secondary antigens, a means for immunotherapeutic treatment of cancer is provided.

REFERENCES:
Likhite, V. V., "Clinical Cancer Immunotherapy: Experience in Breast and Lung Cancer", Immunocancerology in Solid Tumors, (Martin, M. and Dionne, L., eds.), pp. 135-141, 1976.
Likhite, V. V., IRCS Medical Science, 4,565, (1976).

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