Antigens and monoclonal antibodies reactive against sporozoites

Drug – bio-affecting and body treating compositions – Lymphokine

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424 85, 435 68, 514 2, 514 6, 514 8, 530350, 530387, 530403, 436548, G01N 3353, C12P 2100, A61K 3900, A61K 4502

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active

047103779

ABSTRACT:
Monoclonal antibodies against sporozites of the Eimeria spp. are obtained by use of hybridoma technology. Specific sporozoite antigens for use as vaccines in the prevention and treatment of coccidiosis and hybridoma cultures producing monoclonal antibodies are described.

REFERENCES:
patent: 4289690 (1981-09-01), Pestka et al.
patent: 4301148 (1981-11-01), Shibata et al.
patent: 4341697 (1982-07-01), Snary
Danforth, Biol. Abst., v 75(b), Jun. 1982, No. 42067, "Development of Hybridoma-Produced Antibodies Directed Against Eimeria tenella and Eimeria mitis.
Nabin, Chem. Abst., v 96, No. 83834f, 1982, "Immunological Control of Parasitic Diseases Through Chemically Pretreated Antigens".
Danforth, J. Parasitol, v 68(3), 1982, Jun., pp. 392-397, "Development of Hybridoma-Produced Antibodies Directed Against Eimeria tenella and Eimeria mitis.
Danforth et al, Poultry Sci., v. 61(7), pp. 1446-1447, Jul. 82, "Crossreactivity of Monoclonal Antibodies Directed Against Various Species of Avian Coccidia".

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