Antigenic proteins and vaccines containing them for prevention o

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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424 88, 424 93, 530806, 530825, C07K 1504

Patent

active

050286943

ABSTRACT:
A purified antigenic protein has been obtained which is capable of inducing in a chicken an immune response conferring protection against infection by Eimeria necatrix or Eimeria tenella. The protein has a molecular weight of about 26,000 and is composed of two polypeptides joined by a disulfide bond. The two polypeptide subunits have molecular weights of about 18,000 and about 8,000, respectively. The gene encoding the protein has been sequenced and the amino acid sequence of the protein deduced therefrom.
The protein and antigenic polypeptides having an amino acid sequence included within the protein may be incorporated into a vaccine for conferring upon a chicken active immunity against infection by E. necatrix or E. tenella.

REFERENCES:
patent: 4189537 (1980-02-01), Martin et al.
patent: 4438097 (1984-03-01), Shirley
patent: 4710377 (1987-12-01), Schenkel et al.
patent: 4874705 (1989-10-01), Andrews et al.

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