Antigenic preparations and isolation of such preparations

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 92, 530806, 530825, A61K 3910, C07K 1504

Patent

active

052370526

ABSTRACT:
The present invention provides novel antigenic preparations comprising proteinaceous material associated with adenylate cyclase activity in cultures of B. pertussis, the said preparations being useful as components of acellular whooping cough vaccines. The invention further provides methods for the isolation of such antigenic preparations.

REFERENCES:
patent: 3141824 (1964-07-01), Dahlstrom
patent: 3395219 (1968-07-01), Millman
patent: 3465078 (1969-09-01), Spiesel
patent: 4248862 (1981-02-01), Ellwood et al.
patent: 4551429 (1985-11-01), Greenspan
Hewlett et al, "Soluble Adenylate Cyclase from the Culture Medium of Bordatella pertussis," J. Bacteriology, Aug. 1976, pp. 890-898.
Chemical Abstract 87:130,172 (1977), Hewlett et al, "Adenyl Cyclase in Bordatella pertussis vaccines", J. Infect. Dis. 1977, 136 (Suppl.); 216-19.
Manclark et al, Bacterial Vaccine, Germonier, ed. Chapter 3, pp. 72-75.
Hewlett et al., PNAS USA 73, 6, 1926-1930, 1976.
Novotny et al., Proceedings of the Third International Symposium on Pertussis, 99-123, 1979.
Endoh et al., Microbiol. Immunol. 24, 2, 95-104, 1980.
Chemical Abstracts 96, 1982, 197728e.
Confer et al., Science 217, 948-950, 1982.
Chemical Abstracts 99, 1983, 170610k.
Imaizumi et al., Infection and Immunity 41, 3, 1138-1143, 1983.
Sato et al., J. Microbiol. Methods 1, 99-109, 1983.
Weiss et al., Infection and Immunity 42, 1, 33-41, 1983.
Chemical Abstracts 101, 1984, 18519q.
Moss et al., Annals of Internal Medicine 101, 653-666, 1984.
Weiss et al., J. Infect. Dis. 150, 2, 219-222, Aug. 1984.
Beesley & Novotny, abstract submitted to Annual Histochemistry Meeting, Royal Microscopical Soc., United Kingdom, 8 Jan. 85.
Montaraz et al., Infection and Immunity 47, 3, 744-751, Mar. 1985.
Novotny et al., Proceedings of the Fourth International Symposium on Pertussis, Geneva, Switzerland, 25-27 Sep. 1984, published in Develop. Biol. Standard 61, 27-41, 1986.
E. Hewlett, et al., J.B.O. Chem., May 8, 1989, 6 pages, Adenylate Cyclase Toxin form Bordetella pertussis.
Paper-Pertussis, p. 69, Nov. 9, 1989.
Staden, Nucleic Acids Research, No. 9, 1982, pp. 2951-2961.
I. G. Charles, et al., Proc. Natl. Acad. Sci. USA, vol. 86, May, 1989, pp. 3554-3558, Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis.
P. Glaser, et al., Molecular Microbiology, 1968, 2(1), The calmodulin-sensitive adenylate cyclase of Bordetella pertussis: cloning and expression in Escherichia coli.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antigenic preparations and isolation of such preparations does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antigenic preparations and isolation of such preparations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antigenic preparations and isolation of such preparations will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2245131

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.