Antigenic preparations and isolation of such preparations

Details Antigenic preparations and isolation of such preparations Antigenic preparations and isolation of such preparations

1994-03-21

1997-07-15

Sidberry, Hazel F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4241841, 4242401, 4242531, 530350, 5303882, A61K 3900, A61K 3910, A61K 3902

Patent

active

056480806

ABSTRACT:
The invention provides a vaccine containing a proteinaceous material derived from the outer membrane of Bordetella pertussis, wherein the proteinaceous material is characterized by a relative molecular weight of 67,000 to about 73,000, preferably 69,000, as determined by 12% (w/w) polyacrylamide gel electrophoresis, and has a proline:glutamic acid ratio of about 1:1, in a pharmaceutically acceptable carrier or adjuvant. The invention also provides a method of inducing an immune response in an individual involving administering the vaccine of the invention to an individual.

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