Antigenic noninfectious HIV-producing cloned T cell

Details Antigenic noninfectious HIV-producing cloned T cell Antigenic noninfectious HIV-producing cloned T cell

1989-09-29

1992-08-18

Nucker, Christine

Chemistry: molecular biology and microbiology

Spore forming or isolating process

436543, 436811, 435 72, 435 724, 435974, 435 693, 435 701, 435 5, C12N 510

Patent

active

051399474

ABSTRACT:
The invention is a cloned T cell prepared by infecting a human T cell, H9, with HTLV-III B, which cloned human T cell is antigenic for HTLV-III B, does not have a syncytium-forming activity, and does not produce infectious HTLV-III B virions.

REFERENCES:
Popovic, et al., Detection, Isolation & Continuous . . . Pre-AIDS Science 224, 497-500, May 1984.
Harada et al., Infection of HTLV-III/LAV in HTLV-I . . . Assay Science 229, 563-566, Aug. 1985.
Tsai et al., Inhibition of HIV Infectivity by Chloroquine, Int. Conf. on AIDS, Jun. 4-9, 1989 Abstract Only.

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