Antigenic materials

Details Antigenic materials Antigenic materials

1984-02-10

1986-06-10

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 88, 424 92, 435 68, 435885, 530806, 530825, 530350, A61K 3909, A61K 3940, C12P 2100

Patent

active

045942447

ABSTRACT:
An antigenic material having a molecular weight of 3800-4500, and useful in the preparation of an anticaries vaccine is produced from a known antigenic material, antigen I/II of molecular weight 185,000 daltons obtained from the culture supernatant of Streptococcus mutans. The smaller molecular weight fraction of the invention contains the same antigenic determinants as the known 185,000 dalton material but the lower molecular weight material can be used with less side effects. The antigenic material can be used for the production of vaccine preparations that could be administered parenterally or by topical application to the gums.

REFERENCES:
patent: 4442085 (1984-04-01), Colman et al.
patent: 4448768 (1984-05-01), Colman et al.
patent: 4521513 (1985-06-01), Russell
J. of Immunology, 135, 1-6 (1985), Lehner et al.
Journal of General Microbiology (1979), 114, 109-151, Russell.
Infection and Immunity, vol. 29, No. 3, 1980, pp. 999-1006, Russell et al.
Infection and Immunity, vol. 28, No. 2, 1980, 489-493, Russell et al.
Biological Abstracts 73, Abstract 39207, 1982.

Affiliated with

Also associated with

Rating

Antigenic materials does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antigenic materials, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antigenic materials will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2405819