Antigenic fragment of human T-lymphotropic virus

Details Antigenic fragment of human T-lymphotropic virus Antigenic fragment of human T-lymphotropic virus

2006-04-25

2006-04-25

Mosher, Mary E. (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C435S320100, C435S069300, C530S350000, C536S023200, C536S023400, C536S023720, C424S187100, C424S192100, C424S207100

Reexamination Certificate

active

07033751

ABSTRACT:
Antigenic fragments of human T-lymphotropic virus (HTLV), their fusion proteins with glutathione S-tranferase (GST) or thioredoxin (Thio), and a process for producing the fusion proteins thereof. The antigenic fragment of HTLV comprises the amino acid sequence of SEQ ID Nos: 3 or 4.

REFERENCES:
patent: 5310876 (1994-05-01), Bayer et al.
patent: 5643174 (1997-07-01), Yamamoto et al.
patent: 6406841 (2002-06-01), Lee et al.
patent: 0 424 748 (1991-05-01), None
patent: 0424748 (1991-05-01), None
patent: 0781848 (1996-12-01), None
patent: 2000-078973 (2000-03-01), None
patent: WO 9639630 (1996-12-01), None
Abbott Murex. Murex HTLV I+II advertisement. [Retrieved on Sep. 30, 2004] from the Internet <URL: http://abbott-murex.com/products/go80.htm>.
Lal, R.B. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 13 (Suppl1):S170-S178, 1996.
Marin et al., “Chimeric Synthetic Peptides Containing Two Immunodominant Epitopes from the Envelope gp46 and the Transmembrane gp21 Glycoproteins of HTLV-1 Virus”, Biochemical and Biophysical Research Communications 289:1-6, 2001.
Marin et al., “Chimeric Synthetic Peptides from the Envelope (gp46) and the Transmembrane (gp21) Glycoproteins for the Detection of Antibodies to Human T-Cell Leukemia Virus Type II”, Biochemical and Biophysical Research Communications 289:7-12, 2001.
Gray et al. “Envelope Gene Sequence of HTLV-1 Isolate MT-2 and its Comparison with Other HTLV-1 Isolates”. Virology 177:391-395, 1990.
Horal et al. “Identification of type-specific linear epitopes in the glycoproteins gp46 and gp21 of human T-cell leukemia viruses type I and type II using synthetic peptides”. Proc. Natl. Acad. Sci. USA 88(13):5754-5758, Jul. 1, 1991.
Palker et al. “Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-1) gp46 and gp21 envelope glycoproteins with env-coded synthetic peptides and a monoclonal antibody to gp46”. Journal of Immunology 142(3):971-978, Feb. 1, 1989.
Tallet et al. “One-step chromatographic purification procedure of a His-tag recombinant carboxyl half part of the HTLV-1 surface envelope glycoprotein overexpressed inEscherichia colias a secreted form”. Journal of Chromatography B 753:17-22, 2001.
Kitze et al. “Human CD+T lymphocytes recognize a highly conserved epitope of human T lymphotrophic virus type I (HTLV-1)j env gp21 restricted by HLA DRB1*0101”. Clin Exp. Immunol. 111:278-285, 1998.
Varma et al. “Enhanced Specificity of Truncated Transmembrane Protein for Serologic Confirmation of Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) and HTLV-2 Infections by Western Blot (Immunoblot) Assay Containing Recombinant Envelope Glycoproteins”. Journal of Clinical Microbiology 33(12):3239-3244, 1995.
Wang et al. “Molecular Cloning, Expression, and Biological Characterization of an HTLV-II Envelope Glucoprotein: HIV-1 Expression Is Permissive for HTLV-II-Induced Cell Fusion”. Aids Research and human Retroviruses 9(9):849-860, 1993.
Yamano et al. “Preferential recognition of synthetic peptides from HTLV-I gp21 envelope protein by HLA-DRN1 alleles associated with HAM/TSP (HTLV-I-associated myelopathy / tropical spactic paraparesis)”. Journal of Neuroimmunology 76:50-60, 1997.
Database www.uniprot.org—Accession No. Q9WJZ9. Nov. 1, 1999.
Database www.uniprot.org—Accession No. Q82316. Nov. 1, 1996.
Database www.uniprot.org—Accession No. Q82317. Nov. 1, 1996.
Database www.uniprot.org—Accession No. 82315. Nov. 1, 1996.
Database www.uniprot.org—Accession No. Q9JFQ4. Oct. 1, 2000.
Database www.uniprot.org—Accession No. Q80806. Nov. 1, 1996.

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