Antigenic epitopes of IgE present on B cell but not basophil sur

Chemistry: molecular biology and microbiology – Spore forming or isolating process

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 7021, 4354722, 530387, 530388, 530389, 424 858, 424 8591, C12N 512, C07K 1528

Patent

active

050913131

ABSTRACT:
Antigenic epitopes associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane are disclosed. For IgE, the epitopes are present on IgE-bearing B cells but not basophils or the secreted, soluble form of IgE. The epitope can be exploited for diagnosis.

REFERENCES:
patent: 4161522 (1979-07-01), Hamburger
patent: 4171299 (1979-10-01), Hamburger
patent: 4683292 (1987-06-01), Hahn
patent: 4714759 (1987-12-01), Whitaker
Lin et al. PNAS USA 78:504-508, 1981.
Ishida et al The Embaj vol. 1:1117-1123, 1982.
Stanworth Mol. Immunol. 21:L1183-1190, 1984.
Stanworth et al. Mol. Immunol. 23:1231-1235, 1986.
Baniyash et al. Eur. J. Immunol. 14:799-807, 1984.
Hoole et al.. Fed. Proc. 46:1345, 1987.
Hoole et al. Fed. Proc. 40:968, 1981.
Schulman et al. Nature 276:269-270, 1978.
Cheng et al. Nature 296:410, 1982.
Roberts et al. Nature 328:731-734, 1987.
Baniyash et al. Eur. J. Immunol. 17:1337-1342.
World et al. "The Murine Immunoglobulin Gene Expresses Multiples Transcipts from a Unique Membrane Exam" to (particularly, p. 895, 2nd column) EMBO 2:887-898 (1983).
Blattner, F. R. & Tucker, P. w. "The Molecular Biology of Immunoglobulin D" Natove 307; 417-422 (1984).
Kearney, J. F. "Hybridomas and Mabs." Fundamental Immunology (1984) 751-766.
Sita et al., "Membrane Bo und and Secretd .beta.A . . . " J. Immunol. 128:712-716 (1982).
Cushley et al. "A Common Mechanism for the Synthesis" of Membrane and Secreted .beta..alpha., .gamma. L. V. and .mu. in Chains Nature 298:77-79 (1982).
Sell, S. et al. "Stuides on Rabbit Lymphoyctes in Vitro" J. Exp. Med. 122:423-44.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antigenic epitopes of IgE present on B cell but not basophil sur does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antigenic epitopes of IgE present on B cell but not basophil sur, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antigenic epitopes of IgE present on B cell but not basophil sur will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1892516

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.