Antigenic compositions and their use for the detection of Helico

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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435 732, 435 792, 435 793, 435 794, 435 795, 436513, 530350, C07K 300, C07K 1300, C07K 1500, C07K 1700

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active

052621561

ABSTRACT:
The invention discloses antigenic compositions and an assay for detecting Helicobacter pylori. The antigenic composition includes a comprehensive mixture of fragments purified from Helicobacter pylori for the detection of Helicobacter pylori infection and/or for monitoring the status of such an infection following treatment. The assay involves an ELISA for urine samples, and includes a kit wherein the antigenic composition is immobilized on a solid support.

REFERENCES:
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Dooley, C. P., Cohen, H., The Clinical Significance of Campylobacter pylori. Annals of Internal Medicine, 108:70-79 (1988).
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von Wuffen, H. et al., Immunoblot analysis of immune response to Campylobacter pylori and its clinical associations. J. Clin. Pathol., 41:653-659 (1988).
Newell, D. G., Rathbone, B. J., Review Article: The serodiagnosis of Campylobacter pyloir infection. Serodiagn. Immunother. Infec. Dis., 3:1-6 (1989).

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