Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1995-05-10
1998-05-19
Hutzell, Paula K.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
4241841, 4242651, 530350, 5303881, 5303882, 5303886, 435 693, 435 681, A61K 3902, A61K 39002, C07K 1600, C12P 2108
Patent
active
057532362
ABSTRACT:
An antigenic composition against S. mansoni comprising an 8 kD peptidic fragment associated with a suitable vehicle, the 8 kD peptidic fragment being obtained by controlled proteolysis using V8 protease of a 28 kD protein obtained from S. mansoni is described.
REFERENCES:
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Cleveland et al, J. Biol. Chem. 252(3):1102-06, 1977.
Vignali et al, Immunol Today 1012):410-416, 1989.
Shes et al, Parasitology 98 Suppl.:S61-S68, 1989.
Scott et al, Immunol Rev. 112:161-182. 1989.
Huqeunel et al, FASEBJ. 44(3):654 Abstract M26, 1985.
Harn et al. 1985. Mol. Biochem. Parasitology. 16:345-54.
Aron 1991. Vaccine. 9:379-94.
Balloul Jean-Marc
Capron Andre
Grzych Jean-Marie
Pierce Raymond
Hutzell Paula K.
Institut Pasteur
Institut Pasteur de Lille
Minnifield N. M.
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