Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1993-07-13
1998-01-06
Ziska, Suzanne E.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 931, 424 933, 424 937, 4241841, 4351723, C12N 1500, A61K 3900, A01N 6300
Patent
active
057051500
ABSTRACT:
Disclosed herein is a method for producing antibodies against an antigen of interest. Animal cells are exposed to both the antigen of interest and a recombinant retroviral vector. The vector contains a combination of oncogenes capable of inducing plasmacytomas. Plasmacytoma formation takes place rapidly and takes place in the presence of the antigen. A very high proportion of the plasmacytomas that are recovered are antigen specific.
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Largaespada David A.
Mishak Harald
Mushinski Joseph F.
Risser, deceased Rex G.
Weissinger Eva M.
The United States of America as represented by the Department of
Wisconsin Alumni Research Foundation
Ziska Suzanne E.
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