Chemistry: molecular biology and microbiology – Vector – per se
Patent
1995-04-24
1997-09-16
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Vector, per se
435693, 4352523, 536 235, 530350, 530395, 530402, 530828, C12N 1512, C12N 1562, C12N 14435, C12N 1482, C12N 121
Patent
active
056680139
ABSTRACT:
An isolated nucleic acid sequence encoding major Yo paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified major Yo antigenic polypeptide and compositions containing the purified major Yo antigenic polypeptide. Further provided by this invention is a monoclonal antibody directed to an epitope on the major Yo paraneoplastic antigenic polypeptide. Compositions containing this monoclonal antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
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Furneaux Henry M.
Posner Jerome B.
Caputa Anthony C.
Sloan-Kettering Institute for Cancer Research
White John P.
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