Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1992-08-13
1994-08-16
Hutzell, Paula K.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
53038885, 5303888, 5303875, 530327, C07K 1300, C07K 500, C07K 1528
Patent
active
053388321
ABSTRACT:
The present invention comprises the epitope recognized by the human monoclonal antibody 16-18, the human tumor antigen containing this epitope, which we have identified, isolated and characterized, and anti-idiotypic antibodies to human MCA 16-88, which comprise the same epitope. The invention also relates to the use of antibodies to the antigen containing this epitope for diagnosis and monitoring of treatment of cancer and to the use of this antigen in the preparation of vaccines to elicit an immune response similar to that obtained against tumor cells containing this epitope.
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Berman Michael L.
Bos Ebo S.
Hanna, Jr. Michael G.
Haspel Martin V.
Pomato Nicholas
Akzo N.V.
Blackstone William M.
Feisee Lila
Gormley Mary E.
Hutzell Paula K.
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