Antigen from schistosomes and process for obtaining same

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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23230B, 260112R, 260112B, 424 12, 424 85, 424 88, 424177, A61K 2900, A61K 3900, A61K 4100, G01N 3316

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active

041501071

ABSTRACT:
The invention relates to a process for obtaining antigens from living adult schistosomes, wherein schistosomes are kept alive for 12 to 96 hours in a sterile physiologically tolerable salt solution, subsequently isolated and extracted with an aqueous medium, as well as diagnostics for bilharziasis infections containing such antigens or corresponding antibodies and their use for the proof of bilharziasis in vivo and in vitro.

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Bueding, PSEBM, vol. 64, 1947, pp. 111-113.
Von Brand, Biochem. of Parasites, Acd. Press, NY, 1966, pp. 19-27, 90.
Senft, J. of Parasitology, vol. 48, 1962, pp. 551-553.
Enders, Rev. de Inst. Med. Trop. Sao Paulo, vol. 16, No. 6, Nov.-Dec., 1974, pp. 305-316.
Higashi, Life Sci, vol. 13, No. 9, 1973, pp. 1211-1220.
Enders et al., J. Parasitology, vol. 56, 1970, p. 420 Ab. No. 754.
Hohorst et al., Bade Dermatitis, De Gelben Hefte, vol. 1, 1972, pp. 8-13.

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