Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1990-02-27
1993-07-13
Russel, Jeffrey E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530362, 530363, 530402, 530406, 424 88, C07K 1506, C08H 100
Patent
active
052274721
ABSTRACT:
An antigen containing 3-methoxy-4-hydroxyphenylethylene glycol and represented by formula (I): ##STR1## (wherein R-NH is the residue of a polypeptide carrier R-NH.sub.2), and a method of producing an antibody to 3-methoxy-4-hydroxyphenylethylene glycol, characterized in that the method comprises immunizing an animal by using the antigen containing 3-methoxy-4-hydroxyphenylethylene glycol. The MHPG antigen of the present invention is capable of producing an MHPG antibody of high specificity. This antibody enables a precise determination of MHPG in specimens such as body fluid.
REFERENCES:
patent: 5145791 (1992-09-01), Zeitvogel et al.
Niklasson et al., Biol. Psychiatry (USA) vol. 19 (8) pp. 1183-1206 (1984) (abstract).
Keeton et al., Science, 211: 586-588 (1981).
Daiichi Radioisotope Laboratories, Ltd.
Russel Jeffrey E.
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