Antigen for early pregnancy test and contraceptive vaccine

Details Antigen for early pregnancy test and contraceptive vaccine Antigen for early pregnancy test and contraceptive vaccine

1980-08-28

1982-01-12

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 2601125R, 260121, 424 1, 424 12, 424 85, 424 88, A61K 39385, A61K 39395, A61K 3944, C07G 700

Patent

active

043104550

ABSTRACT:
Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the .beta.-subunit of human chorionic gonadotropin which has been modified by cleaving and optionally conjugating the thus modified .beta.-subunit with a protein or hapten capable of enhancing the immunogenetic potency of the antigen. The antigens are also useful for the contraceptive purposes to terminate pregnancy.

REFERENCES:
patent: 3903262 (1975-09-01), Pappenhagen et al.
patent: 3992514 (1976-11-01), Donini
patent: 4016250 (1977-05-01), Saxena
patent: 4161519 (1979-07-01), Talwar
Biochem. Biophys. Res.-Comm., vol. 70, No. 2, May 17, 1976, pp. 525-532, Bahl et al.
Proc. Nat. Acad. Sci. USA, vol. 72, No. 1, Jan. 1976, pp. 218-222, Talwar et al.
Chem. Abstracts, vol. 85, No. 11, Sep. 13, 1976, p. 184, 73750j, Bahl et al.

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