Antigen for early pregnancy test and contraceptive vaccine

Details Antigen for early pregnancy test and contraceptive vaccine Antigen for early pregnancy test and contraceptive vaccine

1978-02-06

1980-11-18

Schafer, Richard E.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

260112B, 424 8, 424 12, G01N 3316, A61K 4300

Patent

active

042345618

ABSTRACT:
Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the .beta.-subunit of human chorionic gonadotropin which has been modified by cleaving and optionally conjugating the thus modified .beta.-subunit with a protein or hapten capable of enhancing the immunogenetic potency of the antigen. The antigens are also useful for the contraceptive purposes to terminate pregnancy.

REFERENCES:
patent: 3903262 (1975-09-01), Pappenhagen et al.
patent: 3992514 (1976-11-01), Donini
patent: 4016250 (1977-05-01), Saxena
Bahl et al., Biochem. Biophys., Res. Comm., vol. 70, No. 2, May 17, 1976, pp. 525-532.
Tawar et al., Proc. Nat. Acad. Sci, USA, vol. 72, No. 1, Jan., 1976, pp. 218-222.
Bahl et al., Chemical Abstracts, vol. 85, No. 11, Sep. 13, 1976, p. 184, Abstract No. 73750j.

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