Antigen derived from human ovarian tumors and radioimmunoassay u

Details Antigen derived from human ovarian tumors and radioimmunoassay u Antigen derived from human ovarian tumors and radioimmunoassay u

1983-01-28

1986-04-22

Wiseman, Thomas G.

Chemistry: analytical and immunological testing

Involving immune complex formed in liquid phase

Separation of immune complex from unbound antigen or antibody

424 11, 436516, 436536, 436537, 436539, 436543, 436547, 436804, 436813, 436815, 436825, 436828, G01N 3356

Patent

active

045842787

ABSTRACT:
Methods for the isolation and purification of an antigen, named NB/70K, from human ovarian carcinomas and radioimmunoassays for the detection of ovarian carcinomas, as well as an antibody specific for NB/70K.

REFERENCES:
Hollinshead, A., Devel. Cancer Research, vol. 1, 543-551 (1979).
Stolbach, L. et al., Devel. Cancer Research, vol. 1, pp. 553-557 (1979).
Bhattacharya, M., Barlow, J. J.; Tumor-Associated Antigen for Cystadenocarcinomas of the Ovary, Nat'l Cancer Inst. Monogr., 42:25-32, 1975.
Bhattacharya, M., Barlow, J. J.; Ovarian Tumor Antigens, Cancer (Phila) 42:1616-1620, 1978.
Bhattacharya, M., Barlow, J. J.; Tumor Markers for Ovarian Cancer, Adv. Surg. Oncol., 2:155-176, 1979.
Burton, R. M., Thermostable Antigens (TA) in Ovarian Cancer, Dev. Cancer Res., 1:541-542, 1979.
Burton, R. M., Hope, N. J., Lubbers, L. M.; A Thermostable Antigen of Human Ovarian Cancer, Fed. Proc., 341:1036, 1975.
Burton, R. M., Hope, N. J., Lubbers, L. M.; A Thermostable Antigen Associated with Ovarian Cancer, Am. J. Obstet. Gynecol., 125:472-477, 1976.
Imamura, N., Takahashi, T., Lloyd, K. O., Lewis, Jr. J. L., Old, L. J.: Analysis of Human Ovarian Tumor Antigens Using Heterologous Antisera: Detection of New Antigenic Systems, Int. J. Cancer, 21:570-577, 1978.
Lloyd, K. O.; Ovarian Cancer Antigen, OVC-2, Dev. Cancer Res., 1:533, 1979.
Lloyd, K. O.; Ovarian Cancer Antigen, OVC-1, Dev. Cancer Res., 1:535, 1979.
Knauf, S., Urbach, G. I.; Purification of Human Ovarian Tumor-Associated Antigen and Demonstration of Circulating Tumor Antigen in Patients with Advanced Ovarian Malignancy, Am. J. Obstet. Gynecol., 127:705-710, 1977.
Knauf, S., Urbach, G. I.; The Development of a Double-Antibody Radioimmunoassay for Detecting Ovarian Tumor-Associated Antigen Fraction OCA in Plasma, Am. J. Obstet. Gynecol., 131:780-787, 1978.
Knauf, S., Urbach, G. I.; Identification, Purification, and Radioimmunoassay of NB/70K, A Human Ovarian Tumor-Associated Antigen, Cancer Res., 41:1351-1357, 1981.

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