Antigen derivatives and processes for their preparation

Details Antigen derivatives and processes for their preparation Antigen derivatives and processes for their preparation

1983-03-21

1986-03-04

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

045740585

ABSTRACT:
The invention relates to novel antigen derivatives comprising an antigen and at least one muramylpeptide covalently bonded thereto, if appropriate via a spacer, to pharmaceutical preparations which contain such compounds and to their use as a vaccine.
The novel antigen derivatives produce a pronounced increase in the immuno-response to the antigen, and in particular also a cell-medicated immunity under clinically acceptable conditions of administration.

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Chem. Abst., 86, 155,893t.
Chem. Abst., 90, 34,099.

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