Antigen delivery system and method of production

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

Reexamination Certificate

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C424S423000, C424S426000, C424S448000, C424S449000, C424S499000, C424S501000, C424S486000, C424S422000, C424S234100, C424S181100, C435S392000, C528S272000, C264S004600, C504S103000, C436S518000, C436S174000, C436S524000, C436S527000, C436S528000

Reexamination Certificate

active

06838089

ABSTRACT:
The present invention concerns polymer particle vaccine delivery systems in which a water insoluble protein antigen, e.g. a lipidated HpaA protein, is incorporated with particles comprising a polymer matrix. The present invention also concerns a method for incorporating such a water insoluble protein antigen with a polymer matrix in order to produce a polymer particle vaccine delivery system. In addition, the invention also provides a vaccine composition comprising the polymer particle delivery system. The vaccine can be used to treat and/or reduce the risk of for example Helicobacter infection.

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