Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2004-12-09
2009-11-17
Mosher, Mary E (Department: 1648)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S300000
Reexamination Certificate
active
07619061
ABSTRACT:
Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.
REFERENCES:
patent: 4946778 (1990-08-01), Ladner et al.
patent: 5055391 (1991-10-01), Montagnier et al.
patent: 5071972 (1991-12-01), Larsen
patent: 5124255 (1992-06-01), Bolling et al.
patent: 5254458 (1993-10-01), Mimms
patent: 5304466 (1994-04-01), De Leys et al.
patent: 5322769 (1994-06-01), Bolling et al.
patent: 5853978 (1998-12-01), Berman et al.
patent: 6153377 (2000-11-01), Devare et al.
patent: 6846905 (2005-01-01), Hackett, Jr. et al.
patent: 0212914 (1987-03-01), None
patent: 0273115 (1988-07-01), None
patent: 0276846 (1988-08-01), None
patent: 0317804 (1989-05-01), None
patent: 0326100 (1989-08-01), None
patent: 0370458 (1989-11-01), None
patent: 0347365 (1989-12-01), None
patent: 0406473 (1991-01-01), None
patent: 0424634 (1991-05-01), None
patent: 0425633 (1991-05-01), None
patent: 0473065 (1992-03-01), None
patent: 0591914 (1994-04-01), None
patent: 0617132 (1994-09-01), None
patent: 0727497 (1996-08-01), None
patent: 2188639 (1997-10-01), None
patent: 8912094 (1989-12-01), None
patent: 9107664 (1991-05-01), None
patent: 9400594 (1994-01-01), None
patent: 9523973 (1995-09-01), None
patent: 9532293 (1995-11-01), None
patent: 9612809 (1996-05-01), None
patent: 9909410 (1999-02-01), None
EMBL X 96526 (from search notes of 08/911,824 dated Jan. 25, 2001).
Rayfield et al. Emerging Infectious Dis. 1996 vol. 2, pp. 209-212.
EMBL and NCBI Accession No. X96526, sequence comparison sheet from 08911824.
Delaporte et al., AIDS 1996, vol. 10, pp. 903-910.
Amino Acid Sequence Comparison dated Jan. 25, 2001 (one two-sided page).
Hampl, H. et al., “First case of HIV-1 subtype O infection in Germany”, Infection, vol. 23, No. 6, Nov. 1995, pp. 369-370.
Kuhnel, H. et al., “Molecular cloning of two West African human immunodeficiency virus type 2 isolates that replicate well in macrophages: A Gambian isolate, from a patient with neuralgic acquired immunodeficiency syndrome, and a highly divergent Ghanian isolate”, Proc. Natl. Acad Sci., USA, vol. 86, Apr 1989, pp. 2383-2387.
Kuhnel, H. et al., “Nucleotide sequence of HIV-2 D194, an isolate from a Gambian case of ‘Neuro-AIDS’, which showed excellent growth in macrophages”, Nucleic Acids Research, vol. 18, No. 20, Aug. 28, 1990, p. 6142.
Shoeman, R.L. et al., “Comparison of Recombinant Human Immunodeficiency Virus gag Precursor and gag/env Fusion Proteins and a Synthetic env Peptide as Diagnostic Reagents”, Analytical Biochemistry, vol. 161, No. 2 (1987) pp. 370-379.
Yuan, Xin et al., “Human Immunodeficiency Virus vpr Gene Enclodes a Virion-Associated Protein”, AIDS Research and Human Retroviruses, vol. 6, No. 11, (1990) pp. 1265-1271.
“Construction of Immunoglobulin Fusion Proteins” , Current Protocols in Immunology, Supp. 4, pp. 10.19.1-10.19.11 (1992) John Wiley and Sons, New York, New York.
“The EBV-Hybridoma Technique and Its Application to Human Lung Cancer”, S.P.C. Cole et al., Monoclonal Antibodies and Cancer Therapy, Alan R. Liss, Inc., New York, New York, pp. 77-96 (1985).
Human Retroviruses and AIDS 1995, G. Meyers et al., Los Alamos National Laboratory, Los Alamos, NM (1995) [Table of Contents (partial)].
J.D. Watson et al. (Eds.), molecular Biology of the Gene, fourth edition, Benjamin/Cummings Publishing Company, Inc., (1987), p. 440.
J. Sambrook et al., Molecular Cloning: A Laboratory Manual, second edition, Cold Spring Harbor Laboratory Press (1989).
P. Charneau et al., “Isolation and Envelope Sequence of a Highly Divergent HIV-1 Isolate: Definition of a New HIV-1 Group”, Virology, vol. 205 (1994) pp. 247-253.
M. Vanden Haesevelde et al., “Genomic Cloning and Complete Sequence Analysis of a Highly Divergent African Human Immunodeficiency Virus Isolate”, Journal of Virology, vol. 68, No. 3 (1994) pp. 1586-1596.
I. Loussert-Ajaka et al., “HIV-1/HIV-2 Seronegativity In HIV-1 Subtype O Infected Patients”, Lancet, vol. 343, (1994) pp. 1393-1394.
L.G. Gurtler et al., “A New Subtype of Human Immunodeficiency Virus Typ 1 (MVP-5180) From Cameroon”, Journal of Virology, vol. 68, No. 3 (1994) pp. 1581-1585.
R. De Leys et al., “Isolation and Partial characterization of an Unusual Human Immunodeficiency Retrovirus from Two Persons of West-Central African Origin”, Journal of Virology, vol. 64, No. 3 (1990) pp. 1207-1216.
CDC, “AIDS Due to HIV-2 Infection-New Jersey”, MMWR, vol. 39 (1987) pp. 33-35.
M.A. Rey et al., Lancet, vol. i, (1987) pp. 388-389.
A.G. Saimot et al., Lancet, vol. i, (1987) p. 688.
A. Werner et al., Lancet, vol. i (1987) pp. 868-869.
I. Loussert-Ajaka et al., “Variability of Human Immunodeficiency Virus Type 1 Group O Strains Isolated from Cameroonian Patients Livig in France”, Journal of Virology, vol. 69, No. 9 (1995) pp. 5640-5649.
M. Peeters et al., “Geographical Distribution of Hiv-1 Group O Viruses in Africa”, AIDS, vol. 11, (1997) pp. 493-498.
F. Denis et al., “Comparison of 10 Enzyme Immunoassays for Detection of Antibody to Human immunodeficiency Virus Type 2 in West African Sera”, Journal of Clinical Microbiology, vol. 26, No. 5 (1988) p. 1000-1004.
W.H. Landschulz et al., “The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins”, Science, vol. 240 (1988) pp. 1759-1764.
H. Kuhnet et al., “Molecular Cloning of Two West African Human Immunodeficiency Virus Type 2 Isolates that Replicate Well in Macrophages . . . ”, Proceedings of the National Acad. Sci., vol. 86, (1989) pp. 2383-2387.
D. Kozbor et al., “The Production of Monoclonal Antibodies from Human Lymphocytes”, Immunology Today, vol. 4, No. 3 (1983) pp. 72-79.
C. Schable et al., “Sensitivity of United States HIV Antibody Tests for Detection of HIV-1 Group O Infections”, Lancet, vol. 344 (1994) pp. 1333-1334.
H. Kuhnet et al., “Nucleotide Sequence of HIV-2D194, an Isolate from a Gambian Case of ‘Neuro-AIDS’, Which Showed Excellent Growth in Macrophages”, Nucleic Acids Research, vol. 18, No. 20 (1990) p. 6142.
M. Gouy et al., “Codon Usage in Bacteria: Correlation with Gene Expressivity”, Nucleic Acids Research, vol. 10, No. 22 (1982) pp. 7055-7074.
L. Gurtler et al., “Reactivity of Five Anti-HIV-1 Subtype O Specimens with Six Different Anti-HIV Screening ELISA's and Three Immunoblots”, Journal of Virological Methods, vol. 51 (1995), pp. 177-187.
V. Gluzman, “SV40-Transformed Simian Calls Support the Replication of Early SV40 Mutants”, Cell, vol. 23 (1981), pp. 175-182.
I. Wilson et al., “The Structure of an Antigenic Determinant in a Protein”, Cell, vol. 37 (1984) pp. 767-778.
H. Hampl et al., “First Case of HIV-1 Subtype O Infection in Germany”, Infection, vol. 23 No. 6 (1995) pp. 369-370.
P.A. Price et al., “Propertied of Chromatography Purified Bovine Pancr atic Deoxyribonuclease”, The Journal of Biol. Chem., vol. 244 No. 4 (1969) p. 917-923.
H.U. Benard et al., “Construction of Plasmid Cloning Vehicles that Promote Gene Expression from the Bacteriophage Lambida pL Promoter”, Gene, vol. 5 (1979) pp. 59-76.
H. Grosjean et al., “Preferential Codon Usage in Prokaryotic Genes: the Optimal Codon-Antlcodon Interaction Energy and the Selective Codon in Efficiently Expressed Genes”, Gene, vol. 18 (1982) pp. 199-209.
Kohler et al.
Brennan Catherine A.
Devare Sushil G.
Golden Alan M.
Hackett, Jr. John R.
Hickman Robert K.
Abbott Laboratories Inc.
Hartnicki Audrey L.
Hill Myron G
Mosher Mary E
Mueller Lisa
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