Antigen-based treatment for adiposity

Details Antigen-based treatment for adiposity Antigen-based treatment for adiposity

1986-03-25

1992-03-17

Kepplinger, Esther L.

Drug, bio-affecting and body treating compositions

Lymphokine

424 89, 424 90, 424 91, 424 92, 424574, 514 21, 530350, 530380, A61K 3900

Patent

active

050967061

ABSTRACT:
A method of preventing, controlling or reducing adiposity in which an animal or human subject is treated with an immunogen which is a modified or unmodified antigenic substance obtainable from adipose tissue of an individual of the same species as the subject or of a species which is closely related phylogenetically to the species of the subject or which is a modified or unmodified antiidiotypic antibody or fragment thereof to an antibody raised against said antigenic substance whereby an immune response is elicited in the subject effective to prevent, control or reduce adiposity.

REFERENCES:
patent: 4526716 (1985-07-01), Stevens
Pillion et al., J. Biol Chem. 225, (1980) pp. 9168-9176.
A. Cryer, Reprod. Nutr. Develop. 25 (1B), 159-164 (1985).
D. J. Pillion et al., J. Biol. Chem. 253, 3761-3764 (1978).
D. J. Pillion et al., J. Biol Chem. 254, 3211-3220 (1979).
R. K. Tume et al., Comp. Biochem. Physiol. 803, 127-134 (1985).
"Feedstuffs" (The Weekly Newspaper for Agribusiness), vol. 57, No. 47. pp. 1 and 23 (Nov. 1985).
Bernard Dixon in "The Guardian" (English daily newspaper), Jan. 31, 1986 p. 23.
A. Cryer et al., J. Develop. Physiol., 6, 159-176 (1984).
Coggrave et al., J. Endocrinology, 102 (Supplement), Abstract No. 41 (1984).
C. E. Futter et al., poster P4 exhibited at University of Nottingham 43rd Easter School, Sutton Bonington, 15-18 Apr. 1985.

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