Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1995-06-06
1999-06-01
Scheiner, Laurie
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241851, 4241301, 4241391, 435 71, 435 792, 435 795, 435 693, 435810, 4352872, 436501, 436518, 530350, 5303871, 5303879, G01N 3353, A61K 39395
Patent
active
059086270
ABSTRACT:
A 69 kD protein, designated PM-1, is expressed in human pancreatic islet cells and a human insulinoma. The amino acid sequence of the protein has been determined. Autoantibodies to the PM-1 protein have been found in sera of prediabetic patients. Natural, synthetic or recombinant forms of the PM-1 protein can be used in immunochemical assays to detect anti-PM-1-autoantibodies and to identify patients at risk of developing diabetes.
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Eisenbarth George S.
Pietropaolo Massimo
Joslin Diabetes Center, Inc.
Scheiner Laurie
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