Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-08-16
2005-08-16
Scheiner, Laurie A. (Department: 1648)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C514S04400A, C424S185100
Reexamination Certificate
active
06930181
ABSTRACT:
A 69 kD protein, designated PM-1, is expressed in human pancreatic islet cells and a human insulinoma. The amino acid sequence of the protein has been determined. Autoantibodies to the PM-1 protein have been found in sera of prediabetic patients. Natural, synthetic or recombinant forms of the PM-1 protein can be used in immunochemical assays to detect anti-PM-1-autoantibodies and to identify patients at risk of developing diabetes.
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Eisenbarth George S.
Pietropaolo Massimo
Fish & Richardson P.C.
Joslin Diabetes Center, Inc.
Scheiner Laurie A.
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