Antigen/antibody specification exchanger

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 71, 435 79, 435 792, 435974, 530324, 530325, 530326, 530327, 530328, 530329, 530330, 530350, C12Q 170

Patent

active

060401370

ABSTRACT:
An antigen/antibody specificity exchanger is disclosed. The exchanger comprises an amino-acid sequence of an antibody which specifically binds to a certain antigen linked to an amino-acid sequence to which a certain antibody binds. Also, a diagnostic reagent comprising an antigen/antibody specificity exchanger is disclosed. The reagent may be used, for example, instead of antisera or monoclonal antibodies in in vitro testing systems, such as immunological tests. Further, a method of treating a disease or disorder caused by a known antigen in an individual in need of an increased number of antigen-specific antibodies is disclosed. The method may be used, for example, to redirect a patient's antibodies against poliovirus to fight HIV infection.

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