Antifungal macrolides and their synthesis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514450, 540145, 549266, 549271, A61K 3133, C07D31300

Patent

active

059487704

ABSTRACT:
There are disclosed novel antifungal macrolides of the formula ##STR1## compositions containing said compounds, methods of using said compounds and a method for synthesizing the compounds.

REFERENCES:
Annals of the NY Academy of Sciences, vol. 544, pp. 128-140 (1988), by H. Achenbach, et al.
J. of Antibiotics, vol. XXXIX, No. 12, pp. 1760-1764 (1986).
J. of Antibiotics, vol. XXXVIII, No. 12, pp. 1806-1809, 1810-1812 (1985).
J. of Antibiotics, vol. XXXIX, No. 7, pp. 1016-1020 (1986).
Achenbach et al., Tetrahedron Letters, 26(50) p. 6167-70, 1985.

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