Antifungal dermatological solution

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31415

Patent

active

049121243

ABSTRACT:
Alcohol/aqueous solutions of certain relatively insoluble imidazole derivatives, particularly micronazole and miconazole nitrate, are prepared to concentrations of at least 1.0 percent by weight active agent. The solutions are pharmacologically acceptable for topical application as the treatment of fungal skin infections and are readily applied by means of a pump sprayer.

REFERENCES:
patent: 3717655 (1973-02-01), Godefroi et al.
patent: 3989815 (1976-11-01), Rajadhyaksha
U.S. Pharmacopeia XX, Supplement 3, pp. 193-195.
Physical and Technical Pharmacy, edited by Burlage, Lee and Rising, McGraw-Hill, pp. 430-433.
Physical Pharmacy, Martin, Swarbrick and Cammarata, pp. 462-465.

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