Antifungal compositions with improved bioavailability

Details Antifungal compositions with improved bioavailability Antifungal compositions with improved bioavailability

2006-07-25

2006-07-25

Wang, Shengjun (Department: 1617)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S464000, C424S474000, C424S475000, C424S489000, C514S254070

Reexamination Certificate

active

07081255

ABSTRACT:
The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.

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